Spectrophotometric Estimation of Olmesartan Medoxomil and Hydrochlorothiazide in Tablet
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چکیده
A simultaneous determination of olmesartan medoxomil and hydrochlorothiazide by absorption ratio spectrophotometric method has been developed in combined tablet dosage form. The method is based on measurements of absorbance at isoabsoptive point. The Beer's law obeys in the range of 10-30 mug/ml for both olmesartan medoxomil and hydrochlorothiazide respectively. The proposed method was validated by performing recovery study and statistically.
منابع مشابه
Derivative and Q-analysis Spectrophotometric Methods for Estimation of Hydrochlorothiazide and Olmesartan Medoxomil in Tablets
Two methods for simultaneous estimation of hydrochlorothiazide and olmesartan medoxomil in combined tablet dosage form have been developed. The first method is the application of Q-analysis method (absorbance ratio), which involves the formation of Q-absorbance equation at 264 nm (isobestic point) and at 271 nm, the maximum absorption of hydrochlorothiazide. The linearity ranges for hydrochloro...
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Corresponding Authors: Miss Trupti B. Solanki PG (QA) Research Scholar Quality Assurance Department, Anand Pharmacy College, Near Town Hall, Anand388 000, Gujarat, India Email: [email protected] Abstract: Aim: To develop and validate two novel spectrophotometric methods for the simultaneous determination of ternary mixture of Olmesartan medoxomil, Amlodipine besylate and Hydrochlorothiazide...
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